The Effect of Zinc Sulphate on the Increase of CD4 T Lymphocytes in HIV/AIDS Patients
|Adhiyanti Asikin1*, Bambang Wirjatmadi2, Joewono Soeroso3 and Erwin Astawa3|
|1Master Program of Public Health Faculty, Airlangga University, Surabaya, Indonesia|
|2Public Health Faculty, Airlangga University, Surabaya, Indonesia|
|3Medical Faculty, Airlangga University, Surabaya, Indonesia|
|Corresponding Author :||Adhiyanti Asikin
Master Program of Public Health Faculty
Airlangga University, Surabaya, Indonesia
E-mail: [email protected]
|Received May 27, 2013; Accepted July 14, 2015; Published July 21, 2015|
|Citation: Asikin A, Wirjatmadi B, Soeroso J, Astawa E (2015) The Effect of Zinc Sulphate on the Increase of CD4 T Lymphocytes in HIV/AIDS Patients. Biochem Physiol S5:003. doi:10.4172/2168-9652.S5-003|
|Copyright: © 2015 Asikin A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.|
People with HIV infection and AIDS requires nutrients that contain macronutrients (carbohydrates, proteins, fats) and micronutrients (vitamins and minerals) in sufficient amount because HIV / AIDS will affect their nutritional status and immune system. HIV infection affect suppress of CD4 T lymphocytes both the quantity and quality. Zinc is known to have a role in increasing CD4 counts in HIV / AIDS patient
This research is experimental with Randomized Pretest Posttest Control Group Design by giving double-blind treatment. The purpose of this study was to analyze the effect of zinc sulphate on CD4 T lymphocytes in HIV / AIDS patients. Population of this study was all outpatients with HIV / AIDS in PIPI units Dr. Soetomo hospital who has earned ARVs. Samples in this study were HIV / AIDS patients from screening results who taken randomly from sub-populations and fulfill inclusion criteria who received ARVs in the last year. Sample of this study divided into two groups, treatment group and control group.
The results of Independent Sample T-test in this study were there are no significant differences CD4 count of respondents between treatment groups who given zinc sulphate supplement and the control group who given a placebo. Most respondents in the treatment group experienced an increase of CD4 count after given an intervention. Results of Chi - Square showing there are a relation between the sample and the difference of CD4 counts.