Dersleri yüzünden oldukça stresli bir ruh haline sikiş hikayeleri bürünüp özel matematik dersinden önce rahatlayabilmek için amatör pornolar kendisini yatak odasına kapatan genç adam telefonundan porno resimleri açtığı porno filmini keyifle seyir ederek yatağını mobil porno okşar ruh dinlendirici olduğunu iddia ettikleri özel sex resim bir masaj salonunda çalışan genç masör hem sağlık hem de huzur sikiş için gelip masaj yaptıracak olan kadını gördüğünde porn nutku tutulur tüm gün boyu seksi lezbiyenleri sikiş dikizleyerek onları en savunmasız anlarında fotoğraflayan azılı erkek lavaboya geçerek fotoğraflara bakıp koca yarağını keyifle okşamaya başlar
Reach Us
+44-3308187254
GET THE APP
Assessment Of Adhesion Response To 3D Printed Materials For Ophthalmic Device Development | 61772
ISSN: 2167-065X
Clinical Pharmacology & Biopharmaceutics
Open Access
Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.
Introduction & Aim: Glaucoma is the leading cause of irreversible visual impairment worldwide. Glaucoma surgical devices fail
due to a scarring response that resulted in fibrous encapsulation surrounding the device preventing aqueous humor drainage.
3D printing technology has the potential to develop personalized ophthalmic devices or organs with improved cost effectiveness
and productivity. Limited experimental data exists as to the biocompatibility response of 3D printed photopolymers. We
performed cell adhesion and protein adsorption studies of 3D printed photopolymers compared to materials used in current
ophthalmic devices (silicone, polytetrafluoroethylene (PTFE) and poly (methyl methacrylate) (PMMA)) to assess 3D printed
materials as a potential route for ophthalmic device development.
Methods: 3D printed materials (n=6) were developed using a high-resolution, desktop stereo-lithography (SLA) 3D printer
and compared to materials used in current ophthalmic devices. Protein adsorption was quantified using a micro bicinchoninic
acid (micro BCA) assay and fluorescein-conjugated bovine serum albumin (FITC-BSA) adsorption. Cell adhesion (monocytes,
fibroblasts) was assessed using alamarBlue, CyQUANT and Live/Dead assays. Data were compared using a two-tailed unpaired
t-test.
Results: 3D printed materials demonstrated low cell adhesion and protein adsorption. Results were similar to those found
with materials used in current ophthalmic devices (P>0.05). However, it was noted that 3D printed materials demonstrated
increased cytotoxicity (P<0.05).
Conclusion: 3D printed photopolymer materials demonstrated a similar biocompatibility response to currently used materials
and may allow for the development of customizable ophthalmic devices or organs. Subsequent testing will determine the
adhesion response to 3D printed materials containing anti-scarring agents.