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In Association with
Bioconjugation studies of GO/Fe3O4 nanocomposites hollow/porous magnetite
4th Annual Conference and Expo on Biomaterials
Amodini Mishra, Bijoy Kumar Kuanr and Tanuja Mohanty
Jawaharlal Nehru University, India
Posters & Accepted Abstracts: J Biotechnol Biomater
Abstract
In this paper, we have synthesized reduced graphene oxide/magnetite (rGO-Fe3O4) nanocomposites by chemical coprecipitation method for a comparative Raman spectroscopic study. The nanocomposites along with its pristine GO and Fe3O4 counterpart were modified covalently with a fluorescently labeled protein. The modification was confirmed using confocal fluorescence microscopy. The GO, Fe3O4 and rGO-Fe3O4 samples were characterized by different spectroscopic and microscopic techniques before and after protein conjugation. A significant enhancement in Raman peaks obtained in case of protein modified rGO-Fe3O4 nanocomposites compared to pristine GO and Fe3O4explains active Surface Enhancement Raman Spectroscopy (SERS) effect. An unusual phenomenon of GO to rGO conversion and vice-versa was noted as a result of covalent protein attachment.Biography
E-mail: fatimafaria45@gmail.com
