Decortication Of Eichhornia Crassipes (pontederiaceae) Fibers For The Production Of Multifilament Non-absorbable Surgical Suture | 13348
Clinical Pharmacology & Biopharmaceutics
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Exhibiting fibrous and antimicrobial characteristics,
(water hyacinth) presents an edge to be used in
medicine. The study aims to provide a new source of multifilament surgical sutures from decorticated petiole fibers of water
hyacinth. The fibers were braided and autoclaved for sterilization. After which, diameter measurement, sterility test, and heavy
metal test were done. Tensile strength, knot strength of the sutures and wound tensile strength were measured using a tensiometer.
Surgical incisions done under anesthesia on dorsolateral areas of six male albino rabbits (
) were sutured. Silk
suture was used as the positive control. Observation was done for 7 days to grade skin reactions. Skin samples were then excised after
euthanasia was done. The samples were then subjected to histopathological examination. Statistical analyses comparing the sutures
were done using independent t-tests. Differences in diameter and tensile strength of both sutures were statistically significant
(p<0.05). Differences in knot tensile strength and wound tensile strength of both sutures were not statistically significant (p>0.05).
Edema, erythema and wicking were absent in both sutures. Dehiscence was seen in 2 wounds with silk suture; 1 wound with water
hyacinth suture. Histopathology showed varied degrees of tissue reaction. However, presence of non-representative samples made
the test inconclusive. Conclusively, sutures from
are physically comparable to silk.
Gironella Rochelle is a 20-year old college student taking BS Pharmacy, Major in Clinical Pharmacy at the University of Santo Tomas, Philippines.
She is a preceptor of the Skin Care Clinic of the Clinical Pharmacy Society. Ms. Gironella and her colleagues made an undergraduate research
focused on innovation of a surgical suture from water hyacinth. Recently, the said undergraduate research won 2nd place in the Student Research
Oral Presentation Competition of the 7th Philippine National Health Research System Week. In addition, with her other colleagues she has also
constructed a systematic review about Clinical Pharmacy Intervention in Geriatric Patients with Polypharmacy
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