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Drug Metabolism And Pharmacokinetics In Modern Drug Discovery, And The Discovery Of Posaconazole | 13302
ISSN: 2167-065X
Clinical Pharmacology & Biopharmaceutics
Open Access
Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.
Drug discovery involves all research activities that are carried out to identify and characterize a new chemical entity (NCE)
that deemed suitable for development as a therapeutic agent. Drug discovery is a complex, dynamic and evolving process.
A successful drug discovery program requires teamwork with excellent scientific and communication skills; and continuous,
effective, and timely participation and interactions of many scientific disciplines. Modern drug discovery has been dictated by
recent advances in chemistry, structural chemistry, molecular biology and genomics, and robotics. NCEs are evaluated for potency
and efficacy, safety, DMPK attributes and pharmaceutical properties. Recent technologies such as
in silico
ADME screening and
metabolomics are quickly gaining ground in the drug discovery landscape. Rational drug design is becoming more prevalent in
the design of new drug candidates. The Discovery of Posaconazole (a triazole antifungal drug) was a result of collaborative efforts
between Chemistry, DMPK, and the Antifungal Discovery Departments, with DMPK playing the leading role. Posaconazole has
been saving lives since it was approved in the US and Europe as well as other parts of the world.
Biography
D
rug discovery involves all research activities that are carried out to identify and characterize a new chemical entity (NCE)
that deemed suitable for development as a therapeutic agent. Drug discovery is a complex, dynamic and evolving process.
A successful drug discovery program requires teamwork with excellent scientific and communication skills; and continuous,
effective, and timely participation and interactions of many scientific disciplines. Modern drug discovery has been dictated by
recent advances in chemistry, structural chemistry, molecular biology and genomics, and robotics. NCEs are evaluated for potency
and efficacy, safety, DMPK attributes and pharmaceutical properties. Recent technologies such as
in silico
ADME screening and
metabolomics are quickly gaining ground in the drug discovery landscape. Rational drug design is becoming more prevalent in
the design of new drug candidates. The Discovery of Posaconazole (a triazole antifungal drug) was a result of collaborative efforts
between Chemistry, DMPK, and the Antifungal Discovery Departments, with DMPK playing the leading role. Posaconazole has
been saving lives since it was approved in the US and Europe as well as other parts of the world.
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