Incidence Of Adverse Drug Reaction Associated With The Use Of Antibiotics At An Orthopedics Hospital | 13292
ISSN: 2167-065X

Clinical Pharmacology & Biopharmaceutics
Open Access

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Incidence of adverse drug reaction associated with the use of antibiotics at an orthopedics hospital

International Summit on Clinical Pharmacy & Dispensing

Tathiana Silva de Souza Martins

ScientificTracks Abstracts: Clinic Pharmacol Biopharmaceut

DOI: 10.4172/2167-065X.S1.002

The National Traumatology and Orthopedics Institute ( NTOI ) is the holder of the maximum hospitals and clinics quality certification granted by the Joint Commission International, since 2006. At NTOI, due to the surgeries characteristics, the patients exposure to infections is pretty significant, demanding the use of antibiotics ( ATBs ) in a large scale and in many cases for a prolonged time, a fact that may extend the possibility of adverse drug reactions ( ADRs ). So, it was objectified to analyse the incidence of ADRs in hospitalized patients associated with ATBs. It is a cohort study. The sample was compounded by 101 adult patients who were hospitalized during January to December 2012. The gathering of data was prospective using medical records and patients interviews. The project was approved by the Research Ethics Committee with human beings from NTOI (n? 0050.0.305.000-10). All patients were submitted to polypharmacy, 31% used more than 2 ATBs and the most prescribed ATB was vancomycin ( 36% ). The incidence of ADRs associated with ATB was 51%, being the majority ( 58% ) considered possible according to Naranjo Algorithm. It was evidenced that 40% of ADRs were caused by rifampicin and 32% by oxacillin. It is concluded that ADRs can present an important negative impact, referring to the patient well- being and the quantity of spending resources. It is necessary that hospitals pharmacovigilance service uses active search as pro- active strategy to minimize the ADRs and their clinic and economic impact.
Tathiana Silva de Souza Martins pursued Ph.D. in the Adult Health Nursing Program at The Sao Paulo University and Masters in Nursing by the Fluminense Federal University. Assistant professor of the Care Nursing Master?s Degree at Fluminense Federal University. Risk manager at The National Traumatology and Orthopedics Institute, responsible for the pharmacovigilance.