Insilico Study Of Mechanism Of Azodye Degradation In Cyanobacterium Nostoc Sp PCC7120 | 4748
Journal of Biotechnology & Biomaterials
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Azodyes poses a great threat on public health due to their toxicity and carcinogenicity. Azoreductase enzyme plays a pivotal role
in the degradation of azodye released by industrial effluents and other sources. However data available on the degradation
pathways in organisms expressing this enzyme is very scarce. Our study attempts to analyze the interaction between the azoreductase
enzyme and other accessory interacting proteins alr2106, alr1063, alr2326 in cyanobacterium Nostoc sp PCC7120. Insilico
methodologies like structure modeling by I-Tasser server, Protein-Protein docking by ClusPRO were instrumental to attain the
objectives. Our investigation shreds light on the possibility that the accessory interacting proteins in cyanobacterium Nostoc sp
could enhance azoreductase activity and thus facilitating better dye degradation. Our future aim is to explore similar prospects in
algae for enhanced azo dye degradation ability.
Nitanjay Singh completed his B.Tech in Biotechnology from SRM University, Chennai and is currently pursuing M.Tech in Chemical Engineering from
National Institute of Technology, Tiruchirappalli. He participated in many national Conferences/seminars. His research interests include waste water
treatment and algal Bioinformatics.
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