Neurological Actions Of Honeybee Products | 107925
Clinical Pharmacology & Biopharmaceutics
Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.
Joint Event on 24th World Congress on Pharmacology & 7th World Heart Congress
Hesham El-Seedi, Shaden Khalifa, Jianbo Xiao, Aida Abd El Wahed, Lei Chenh Mohamed Farag and Ghulam Abbas
Uppsala University, SwedenMenoufia University, EgyptUniversity of Karachi, PakistanStockholm University, SwedenKarolinska Institute, SwedenUniversity of Macau, ChinaAgricultural Research Centre, EgyptFujian Agriculture and Forestry University, ChinaCairo University, EgyptThe American University in Cairo, EgyptZiauddin University, Pakistan
Statement of the Problem: According to the World Health Organization, two billion people will be aged 60 years or
older by 2050. Aging is a major risk factor for a number of neurodegenerative disorders. These age-related disorders
currently represent one of the most important and challenging health problems have impact on the economic and
social. Therefore, much attention has been directed towards the design and development of neuroprotective agents
derived from natural sources.
The honeybees (Apis mellifera L.) have several products, including honey, propolis, royal jelly, bee venom, and bee
pollen. Bee products meet the criteria of being natural products that have long-recognized medicinal properties.
Historically, bee products nutritional and medicinal values have been considered for thousands of years by Ancient
Egyptian, Persians, Romans and Chinese in supplementary nutrition and alternative diets. Bee products are often
sold as nutritional supplements and/or health products, and with potential anticancer, antimicrobial activities,
antioxidant, anti-nociceptive, and anti-inflammatory. Bee products polyphenols have neuroprotective actions via
quench biological reactive oxygen species that cause neurotoxicity and aging as well as the pathological deposition
of misfolded proteins, such as amyloid beta.
In the current talk will concerned on the neuroprotective of bee products and its ingredients against neurogernatives
diseases including Alzheimer???s disease, Parkinson???s disease, multiple sclerosis, amyotrophic lateral sclerosis and
1. Biotech N, Corporation M, Road J, Gung C, Hospital M, Science M, Health, N (2007). Propolin G, a
prenylflavanone, isolated from Taiwanese propolis, induces caspase-dependent apoptosis in brain cancer cells.
Journal of Agricultural and Food Chemistry, 55: 7366???7376.
2. Giampieri F, Quiles JL, Orantes-Bermejo FJ, Gasparrini M, Forbes-Hernandez TY, Sánchez-González C,
Battino M (2018). Are by-products from beeswax recycling process a new promising source of bioactive
compounds with biomedical properties? Food and Chemical Toxicology 112:126???133.
3. Kumar A, Sehgal N, Kumar P, Padi SSV, Naidu P. (2008). Protective effect of quercetin against ICV colchicineinduced
cognitive dysfunctions and oxidative damage in rats. Phytotherapy Research 22: 1563???1569.
4. Squillaro T, Schettino C, Sampaolo S, Galderisi U, Di Iorio G, Giordano A, Melone MAB (2018). Adult-onset
brain tumors and neurodegeneration: Are polyphenols protective? Journal of Cellular Physiology, 233:3955???
5. Tomás A, Falcăo SI, Russo-almeida P, Vilas-boas M (2017). Potentialities of beebread as a food supplement
and source of nutraceuticals: Botanical origin , nutritional composition and antioxidant activity. Journal of
Apicultural Research 8839.
6. Unno K, Takabayashi F, Yoshida H, Choba D, Fukutomi R, Kikunaga N, Hoshino M (2007). Daily consumption
of green tea catechin delays memory regression in aged mice. Biogerontology 8: 89???95.
Hesham R. El-Seedi working in the area of isolation, structure elucidation and synthesis of biologically active natural products from medicinal plants, marine and bee products. Recently, we started also a project on nanoparticles synthesis. Prof. Hesham is a former fellow of the Japanese Society of Promotion of Science (JSPS), Faculty of Science and Technology, Keio University, Japan, under direction of Prof. Shosuke Yamamura and Prof. S. Nishiyama. Throughout his carrier, he worked in pioneer internationally recognized laboratories including Geneva University, Switzerland, in collaboration with Prof. Kurt Hostettmann, Kunglia Tekniska Högskola (KTH), Stockholm, Sweden (since 2007), Faculty of Pharmacy, Uppsala Biomedical Center, Uppsala University, Sweden and Menoufia University, Egypt. He was appointed as Adjunct Faculty Professor at the International Center for Chemical and Biological Sciences (ICCBS), Karachi, Pakistan, 2017 and was rewarded two Swedish Research Links grants for the 2017-2019.He has published peer-reviewed international research articles and scientific papers, reviews, chapters in Peer-Reviewed International Journals
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals