Clinical Pharmacology & Biopharmaceutics
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This study sought to evalute the quality of life (QoL) among patients undergoing anticoagultaion therapy and to
identify the factors impacting their health.
A cross sectional descriptive study was undertaken with atrial fibrillation patients undergoing anticoagulation therapy.
A convienience sample of 339 patients were identified at Anticoagulation Clinics of two public hospitals in Penang, Malaysia. A
bilingual specific instrument; Duke Anticoagulation Satisfaction Scale (DASS) and a generic instrument; the European Quality
of Life scale (EQ-5D) were used for data collection. ANOVA or t-test were used to detect the differences between continuous
variables among the groups.
Patients on warfarin therapy showed good perception of QoL. The DASS results presented an average score of 70.8 (?19.8),
EQ-5D descriptive mean average score was 0.80 (?0.26) and EQ-VAS mean score was 63.3 (?16.3). However, this perception was
influenced positively by age, education level, and occupation and negatively by sex gender and previous hemorrhagic event.
warfarin therapy is not usually associated with a significant decrease in perceived health, unless a bleeding episode
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