alexa The Evaluation Of Renoprotective Effect Of L-Carnitine Against Gentamicin Nephrotoxicity
ISSN: 2167-065X

Clinical Pharmacology & Biopharmaceutics
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

2nd International Summit on Clinical Pharmacy
December 02-03, 2014 DoubleTree by Hilton Hotel San Francisco Airport, USA

Sabah Akrawi
ScientificTracks Abstracts: Clinic Pharmacol Biopharm
DOI: 10.4172/2167-065X.S1.006
Abstract
The protective effect of L-Carnitine on the gentamicin nephrotoxicity was investigated in experimental animal model. Male Wister 200-300 g rats were distributed randomly into four groups, control group, L-Carnitine treated group, Gentamicin treated group, and L-Carnitine + Gentamicin treated group. The result showed that gentamicin nephrotoxicity in rats is detected by significant plasma creatinine, urea and zinc changes in serum and renal tissue. L-Carnitine is able to ameliorate the renal functions and restore the zinc status. Zinc serum level in the gentamicin treated group is 115 μg/dl, while it is 129 μg/ dl in the Gentamicin + L-Carnitine treated group, and Zinc tissue level in the Gentamicin treated group is 14.6 μg/dl, while it is 17.89 μg/dl in the Gentamicin + L-Carnitine treated group. The possibility of scavenging property of L-Carnitine against peroxy radical is via restoring zinc status implicated.
Biography
Sabah Akrawi, PhD, graduated from the College of Pharmacy/University of Kentucky/USA. He is an Assoc. Prof. of Clinical Pharmacokinetic and Biopharmaceutic and a faculty member at the College of Clinical Pharmacy/King Faisal University/KSA. He supervised 17 postgraduate pharmacy students, and has published more than 24 articles. He is a member of the scientific council of the KFU and chaired many defense committees for graduation of graduate students.
image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords