E-ISSN: 2314-7326
P-ISSN: 2314-7334

Journal of Neuroinfectious Diseases
Open Access

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Alzheimers Disease: The Novel Finding of Intracellular Biofilms

Herbert B Allen*, Rina Allawh, Andrew Touati, Christos Katsetos and Suresh G Joshi

Department of Dermatology, Drexel University College of Medicine, Philadelphia, USA

*Corresponding Author:
Herbert B Allen
Department of Dermatology, Drexel University College of Medicine
219 N. Broad St, 4th floor, Philadelphia, PA 19107, USA
Tel: 2157625550
Fax: 2157625570
E-mail: Herbert.Allen@drexelmed.edu

Received Date: March 28, 2017; Accepted Date: May 10, 2017; Published Date: May 12, 2017

Citation: Allen HB, Allawh R, Touati A, Katsetos C, Joshi SG (2017) Alzheimer’s Disease: The Novel Finding of Intracellular Biofilms. J Neuroinfect Dis 8:247. doi: 10.4172/2314-7326.1000247

Copyright: © 2017 Allen HB, et al. This is an open-access article distributed under the terms of the creative commons attribution license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

We previously have found biofilms in the hippocampi of Alzheimer’s disease (AD) post mortem brain specimens. We had seen them in an extracellular location and noted them to be present in the areas of pathological plaque formation. Other investigators have found the presence of spirochetes (Lyme and dental) in affected (AD) brains, and these have been correlated with Treponema pallidum. In a recent historical comparison of the pathology of syphilis, the histological findings of syphilis and AD were shown to be exactly the same. Further, spirochetes have been cultured from the affected brains and have been found to make biofilms and beta amyloid precursor protein. Utilizing the same pathological methods as in our prior study, we have found biofilms in an intracellular location. The similarity of this finding to other diseases has been presented; and, the impact of the “intra” versus the “extra” cellular location is discussed.

Keywords

Top