Cerebral Aneurysm in Lyme Neuroborreliosis with Regression After Medical TreatmentJonathan Tiu1*, Richard M Hanson2 and Robert Staudinger2
- *Corresponding Author:
- Jonathan Tiu
Department of Neurology
School of Medicine, New York University, USA
E-mail: [email protected]
Received date: May 27, 2017; Accepted date: June 13, 2017; Published date: June 16, 2017
Citation: Tiu J, Hanson RM, Staudinger R (2017) Cerebral Aneurysm in Lyme Neuroborreliosis with Regression After Medical Treatment. J Neuroinfect Dis 8: 252. doi:10.4172/2314-7326.1000252
Copyright: © 2017 Tiu J, et al. This is an open-access article distributed under the terms of the creative commons attribution license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Lyme disease in the United States is caused predominantly by the spirochete Borrelia burgdorferi and affects multiple organ systems. Lyme Borreliosis infrequently involves the peripheral and central nervous system, and the term Neuroborreliosis is used for the latter case. The most common manifestations of Neuroborreliosis include cranial neuropathy and lymphocytic meningitis. It can also cause cerebral vasculitis leading to both wall thickening and endothelial obliteration. Other manifestations include stroke, with over 50 documented cases, and rarely nonaneurysmal subarachnoid hemorrhage and intraparenchymal hemorrhage.
Intracranial aneurysm detected in the setting of Lyme Borreliosis infection has been previously documented in four cases [3,4]. However, the existence of a causal relationship between Lyme infection and intracranial aneurysm has been debated. We discuss these cases, and present our own case of a man with Lyme Neuroborreliosis with an intracranial aneurysm which regressed upon completion of treatment with ceftriaxone.