Parechovirus Sepsis and Meningitis in a Neonatal Intensive Care Unit
|Katie Fritz*, Vijender Karody and Susan Cohen|
|Medical College of Wisconsin, USA|
|Corresponding Author :||Katie Fritz
Instructor, Medical College of Wisconsin
Pediatrics, 999 N. 92nd St.
Suite 410, Milwaukee, WI 53226, USA
Tel: 414-429- 2942
E-mail: [email protected]
|Received July 29, 2015; Accepted September 21, 2015; Published September 24, 2015|
|Citation: Fritz K, Karody V, Cohen S (2015) Parechovirus Sepsis and Meningitis in a Neonatal Intensive Care Unit. J Neuroinfect Dis 6:187. doi:10.4172/2314- 7326.1000187|
|Copyright: ©2015 Fritz K, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.|
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The majority of febrile neonates have negative bacterial cultures and presumed viral infections. During November 2014, four febrile neonates in southeastern Wisconsin required intensive care admission for human parechovirus (HPeV) infection in the blood and/or cerebral spinal fluid (CSF). Both vertical and horizontal transmission led to disease, and a variety of signs and symptoms, including tachycardia, hypotension, neutropenia, rash and irritability accompanied fever. All neonates recovered clinically, although concern for neurodevelopmental delay remains for those with meningoencephalitis. This case series describes the presentation and short-term outcomes of neonates requiring intensive care for HPeV infections.