alexa Abstract | Naturally Occurring Enzyme Inhibitors: A Smart Way to Fight against Micro- Inflammation in Human Gut
ISSN: 2381-8727

International Journal of Inflammation, Cancer and Integrative Therapy
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access


Human body is a reservoir for microorganisms, the majority of which resides in the gastrointestinal tract. The diverse micro biota helps to speed up the metabolic processes such as digestion along with providing protection against infections. A balanced diet plays major role in maintaining the balance of gut flora, which could otherwise lead to Dysbiosis. Dysbiosis is an inflammatory condition caused by the over production of bacterial nitroreductase, azoreductase and beta-glucuronidase enzymes. In the following article the active sites of all three enzymes along with their inhibitors were studied. One inhibitor against nitroreuctase, two against azoreductase and three against beta-glucuronidase were selected and docking was done. The inhibitors blocked the enzymes activity. These inhibitors can be obtained from natural food sources to attain a balanced microbial flora resulting in a better metabolism.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Rabail Razi, Zainab Mir, Rimsha Dilshad, Fatima Tuz Zahra and Atif AB*


Aitroreductase, Azoreductase, Beta-glucuronidase, Dysbiosis, Human gut microinflammation, Nicotinamide, Riboflavin, Silymarin, beta-glucuronidase enzymes, microorganisms, lipopolysaccharide, inflammation

Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version