alexa Abstract | Neurological Complications of Novel Influenza A (H1N1) pdm09 Infection: Report of Two Cases and a Systematic Review of the Literature
E-ISSN: 2314-7326
P-ISSN: 2314-7334

Journal of Neuroinfectious Diseases
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access


Background: Neurological complications of Influenza A (H1N1) pdm09 in adults are rarely reported in the literature. The aim of this study is to report a case of Influenza A (H1N1) pdm09 acute necrotizing encephalitis (ANE) and another case of acute hemorrhagic leukoencephalopathy (AHLE) and to review the neurological complications of this disorder in adults. Methods: We conducted a search on Medline, Ovid, EMBASE, ProQuest and PubMed databases using the key words (neurological complications of H1N1 in adults). We also added to the search results those articles which were not found in the search but exist in the literature under different search words. Only papers written in English published from March 2009 to December 2015 were included. Demographic data and clinical diagnosis of neurological complications and outcomes in adults including death, neurological sequalea or recovery after influenza A (H1N1) pdm09 infection have been reviewed. Results: we included 37 articles presenting a total of 261 adult patients with neurologic complications following Influenza A (H1N1) pdm09 infection. In addition, a case of influenza A (H1N1) pdm09 acute necrotizing encephalitis (ANE) and another case of acute hemorrhagic leukoencephalopathy (AHLE) arising from our own neurological practice were also included. Conclusion: In conclusion, this study demonstrates that influenza A (H1N1) pdm09 is both a pandemic and a seasonal (sporadic) disease. We speculate that most of the neurological complications are immune mediated and calling for further studies to test for the potential benefits of early steroids use in the disease. We are calling for an international collaboration and registry for Influenza A (H1N1) pdm09 infection.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Hussein Algahtani, Bader Shirah, Sulaiman Alkhashan and Raafat Ahmad


Nervous System, Viral Infection, Fungal Infection, Neuroinfectious Agents, Non-Polio Enterovirus Infections, Opisthorchis Infection,Sinus Infections,Central nervous system vasculitis,Central nervous system vasculitis

Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version