Ewelina Nycz | OMICS International
ISSN: 2161-0681

Journal of Clinical & Experimental Pathology
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Ewelina Nycz


Changes in the Vascular Extracellular Matrix as a Potential Cause of Myocyte Loss via Anoikis in Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy

Objective: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a generalized vasculopathy caused by mutations in the NOTCH3 gene, leading to degeneration and loss of vascular smooth muscle cells (VSMC). The relationship between NOTCH 3 mutations and VSMC death is unknown. One possible cause of myo... Read More»

Dorota Dziewulska, Ewelina Nycz and Cecylia Rajczewska-Oleszkiewicz

Research Article: J Clin Exp Pathol 2017, 7: 332

DOI: 10.4172/2161-0681.1000332

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article