Kazunari K Yokoyama | OMICS International
ISSN: 2329-6879

Occupational Medicine & Health Affairs
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Kazunari K Yokoyama

Graduate Institute of Medicine, 100 Shih-Chuan 1st Road, San-Ming District, 807 Kaohsiung

Two-hit Reprograming of Induced Pluripotent Stem Cells

Endogenous and exogenous stresses produce reactive oxygen species (ROS) in cells, and these can cause DNA damage, apoptosis, autophagy, and senescence. The reprogramming of somatic cells to produce induced pluripotent stem cells (iPSCs) initially requires ROS production and then represses the endogenous expression of tumor suppressor factors such a... Read More»

Kazunari K Yokoyama

Commentary: Occup Med Health Aff 2014, 2:168

DOI: 10.4172/2329-6879.1000168

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article

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