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Cancer is defined as the uncontrollable growth of cells that invade and cause damage to surrounding tissue. Oral cancer appears as a growth or sore in the mouth that does not go away. Gum cancer or oral cancer, which includes cancers of the lips, tongue, cheeks, floor of the mouth, hard and soft palate, sinuses, and pharynx (throat), can be life threatening if not diagnosed and treated early. Oral cancer accounts for roughly two percent of all cancers diagnosed annually in the United States. Approximately 36,500 people will be diagnosed with oral cancer each year and about 7,900 will die from the disease. On average, 61 percent of those with the disease will survive more than 5 years.
Oral Leukoplakia or oral cancer
Important research into oral and oropharyngeal cancers is taking place in many university hospitals, medical centers, and other institutions around the country. Each year, scientists find out more about what causes the disease, how to prevent it, and how to improve treatment.
One of the changes often found in DNA of oral cancer cells is a mutation of the TP53 gene. The protein produced by this gene (called p53) normally works to prevent cells from growing too much and helps to destroy cells with too much damage for the cells to repair. Changes in the TP53 gene can lead to increased growth of abnormal cells and formation of cancers. Some studies suggest that tests to detect these gene changes may allow oral and oropharyngeal tumors to be found early. These tests may also be used to better find cancer cells that may have been left behind after the tumor is removed and to determine which tumors are most likely to respond to oral surgery .
Journal of Oral Hygiene & Health always promote researchers and professionals in this field to present their work and share worldwide with our journal. All the article and related case reports are welcome in this area. For any issue, or information please contact Journal office at email presented below.
Our special issue based on Oral Biofilm and Oral Surgery
And keeping this in mind Journal of Oral Hygiene and Health is working on special issue based on “Oral Surgery” and “Oral Biofilm (periodontal diseases)” and invite all quality authors to make submission towards it till 30th of March 2016.
Eman H.Abdel-Rahman Induction of protective cellular and humoral responses against fasciolosis in rabbits using immunoaffinity fraction of Fasciola gigantica excretory secretory products PPT Version | PDF Version