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Melfi F | OMICS International
ISSN: 2161-0681

Journal of Clinical & Experimental Pathology
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Melfi F


TERT Promoter Mutations and Tert Expression in Early-Stage (T1N0M0) Non-Small Cell Lung Cancer (NSCLC)

Background: The mutations detected in the promoter of the telomerase reverse transcriptase (TERT) gene,namely C228T and C250T, were first identified in melanoma and subsequently in several cancer models, notably glioma, thyroid cancer and bladder cancer. Recent findings demonstrate that mutation of the TERT promoter may be one of the most common ge... Read More»

Giordano M, Macerola E, Boldrini L, Giannini R, Servadio A, Alì G, Melfi F, Lucchi M, Bertoglio P, Mussi A and Fontanini G

Research Article: J Clin Exp Pathol 2015, 5: 248

DOI: 10.4172/2161-0681.1000248

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