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ISSN: 2161-0681

Journal of Clinical & Experimental Pathology
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Xiangchun Li

People’s Republic of China

Secreted Clusterin (sCLU) Gene Silencing Enhances Chemosensitivity of A549 Cells to Cisplatin through AKT and ERK1/2 Pathways In Vitro

Several studies have shown Secreted Clusterin (sCLU) silencing directed against sCLU mRNA in sCLU-rich lung cancer cell lines sensitized cells to chemotherapy. However, the molecular mechanisms underlying the effect of sCLU silencing on lung cancer cell chemosensitivity is not known. In the present study, we aimed to determine that vector expressin... Read More»

Mei Wang, Xiangchun Li and Zongxiu Yin

Research Article: J Clin Exp Pathol 2014, 4: 162

DOI: 10.4172/2161-0681.1000162

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article