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A Langerhans Cell Histiocytosis In Its Rare Letterer-Siwe Form In A Child Mimicking Osteoarthritis: A Case Report And Literature Review | 78608
ISSN: 2161-119X

Otolaryngology: Open Access
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A Langerhans cell histiocytosis in its rare Letterer-Siwe form in a child mimicking osteoarthritis: A case report and literature review

4th International Conference on Rhinology and Otology

Bouali Mustapha, H Mezhoud, H Soltani and I Fergoug

Oran University Hospital, Algeria

Posters & Accepted Abstracts: Otolaryngol

DOI: 10.4172/2161-119X-C1-023

Abstract
Langerhans cell histiocytosis (LCH) is a group of three rare diseases (annual incidence less than 4/1000.000 H) with increasing aggressiveness respectively: Eosinophilic granuloma (unifocal solitary osteolytic lesion), Hand-Schuller-Christian disease (multifocal lesion) and Letterer-Siwe disease (the most aggressive, disseminated disease with systemic manifestations). Th e bone is most commonly involved with a predilection for the skull. Some cases of temporal bone localizations have been described in the literature. We report a case of an 18-month child presenting a LCH of the temporal bone misdiagnosed at the beginning as osteoarthritis. In fact, the child presented a retro-auricular swelling with infl ammatory characters, fever and otorrhea. Th e exploration before surgery revealed besides the extensive temporal lesion, hematologic perturbations, a splenomegaly and a hepatomegaly. Th e histopathology confi rmed the diagnosis of a LCH. We describe the diagnosis challenges, the surgical diffi culties and the therapeutic response of the child.
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