alexa Enhanced Anti-inflammatory Activity Of Brown Seaweed Laminaria Japonica By Fermentation Using Bacillus Subtilis
ISSN: 2332-2608

Journal of Fisheries & Livestock Production
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

6th Global Summit on Aquaculture and Fisheries 2017
May 25-26, 2017 Osaka, Japan

Wen-Jung Lu, Hong-Ting Victor Lin, Guo-Jane Tsai, Chien-Te Chou, Hsin-I Hsiao and Pai-A Hwang
National Taiwan Ocean University, Taiwan
Genomics Research Center - Academia Sinica, Taiwan
Posters & Accepted Abstracts: J Fisheries Livest Prod
DOI: 10.4172/2332-2608-C1-009
Abstract
Most studies on the anti-inflammatory effects of Laminaria japonica have investigated bioactive ingredients that have been extracted from Laminaria using organic solvents. However, to avoid the toxicity and environmental issues caused by the solvent used for extraction, increasing attention has focused on fermentation using microorganisms as a green bioconversion process for producing bioactive compounds. In this study, fermentation with Bacillus subtilis, where the cultivation parameters and nutrient additives were optimized to achieve the greatest inhibition of lipopolysaccharide (LPS)-induced nitric oxide (NO) production was found to enhance the anti-inflammatory effects of L. japonica. Fermentation by B. subtilis using a 5% (w/v) L. japonica suspension as the sole carbon source, 2% additional nitrogen source, a starting pH of 6, and incubation at 150 rpm at 37°C for 72 h yielded the best anti-inflammatory effects, as LPS-induced NO production decreased to 27.6% ± 5.2%. The macrophages treated with the fermented L. japonica product inhibited the LPS-induced production of reactive oxygen species (ROS) and NF-κB (p65) phosphorylation in a concentration-dependent manner. Thus, our results show that L. japonica products generated by an optimized fermentation process designed to enhance anti-inflammatory effects by decreasing ROS production, NF-κB (p65) phosphorylation, prostaglandin E2, and NO production in macrophages.
Biography

Wen Jung Lu is a PhD student of National Taiwan Ocean University, Taiwan. Her topic is about the antibiotic resistance of microorganisms, and also doing the bioactive compounds in algae. She has obtained the scholarship from National Science Council, Taiwan; the topic is ‘Bioactivity of beta-1, 3-xylan extracted from seaweed by using beta-1, 3-xylanase express from E. coli. Moreover, she is working on the phycobiliproteins and also obtained the scholarship from the Haiden Foundation, Taiwan. She is a competent researcher and she can work well with teams.

Email: [email protected]

image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

mathematics_physi[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords