Journal of Clinical & Experimental Pathology
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is an intracellular pathogen of great economic importance affecting macrophages. The present study revealed
that bovine and murine macrophages present a significant difference in their ability to produce various antibrucella
components such as lysozyme, reactive oxygen species, reactive nitrogen intermediates and pro-inflammatory cytokines. The
differential production of these components explained the differential
killing ability of these species that was measured
in terms of intramacrophagic survival of
in murine and bovine macrophages.
, Cell stimulation, Cytokines, Murine macrophages.
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