Journal of Clinical & Experimental Pathology
Open Access

Abstract

Aims: Frozen section diagnosis provides surgeons, physicians and pathologists a provisional diagnosis to plan out their management plan. By this study, we intended to evaluate the importance of intraoperative consultation-Frozen Section (FS) diagnosis in CNS tumors. In this study, the diagnostic accuracy and the various limitations of using FS diagnosis of CNS tumors were determined. Methods & Material: In study, we analyzed retrospectively the results of FS and final diagnoses of all CNS tumors were made at our institute for duration of one year from July 2014 to June 2015. Results: We studied 252 cases of age group from 1 to 76 years. Out of which, 155 (61.50%) cases had complete concordance between FS and final diagnosis, 77 (30.5%) cases had partial concordance and 20 cases (8.0%) were discordant. Considering the concordant and partially concordant cases, the accuracy rate was 92.0%, sensitivity was 93.42%, specificity was 91.66% and positive and negative predictive values were 94.66% and 59.45%, respectively. Conclusions: A Kappa agreement score of 0.75 (substantial agreement score) showed high concordance for FS results with permanent section. We came to final conclusion that high sensitivity and specificity was seen with FS diagnosis in the cases of CNS tumors.

Biography

Mitul Modi has completed his MBBS degree from Gujarat University and has recently completed Postgraduate studies from Gujarat University, Gujarat Cancer & Research Institute. He has published/presented around 10 papers and 10 or more papers submitted in reputed journals for publication.

Email: mitul.modi7@gmail.com