Morphological Features Of Changes Of Various Types Of Grafts In Patients Who Died After Coronary Artery Bypass Graft Surgery From Isolated Coronary Heart Disease And Associated With Hypertensive Disease | 78647
ISSN: 2161-0681

Journal of Clinical & Experimental Pathology
Open Access

Like us on:

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Morphological features of changes of various types of grafts in patients who died after coronary artery bypass graft surgery from isolated coronary heart disease and associated with hypertensive disease

13th European Pathology Congress

Ruzanna Petrosyan

Beirut Arab University, Lebanon

Posters & Accepted Abstracts: J Clin Exp Pathol

DOI: 10.4172/2161-0681-C1-038

Objectives: Vascular graft failure is one of the most common finding in patients undergoing coronary artery bypass graft (CABG) surgery and still remains the major problem after surgery. The aim of the present study was to investigate features of pathomorphological changes in different type of grafts after CABG in patients with isolated coronary artery disease and associated with hypertensive disease. Materials & Methods: Histopathological study was performed on 207 fragments of autopsy sections of autoarterial and autovenous grafts using light microscopy. Results: It is shown that the condition of the vascular wall is dependent on hemodynamics leading to degenerative changes of the graft as a result of destructive and proliferative processes in the intima and the middle layer. Active replacement of smooth muscle cells of the media by fibrous tissue and then connective tissues leads to thickness of the vascular wall, stenosis on one hand and on the other hand development of unstable atheromatous plaques. Conclusions: Morphological changes of the venous grafts in patients had undergone CABG and had died after surgery from coronary heart disease associated with hypertonic disease were more acute with more aggressive course of atherosclerotic changes with diffuse proliferation of processes and formation of unstable plaques.