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Urinary tract infections after stroke: A longitudinal study among stroke outpatients and inpatients at the Korle-Bu Teaching Hospital in Ghana
12th International Conference on Pediatric Pathology & Laboratory Medicine
Eric S Donkor, Samuel Darkwah and Albert Akpalu
University of Ghana, Ghana
ScientificTracks Abstracts: J Clin Exp Pathol
Abstract
Background: In Africa, little is known about urinary tract infection (UTI) in relation to stroke patients. The aim of the study was to investigate the epidemiology of UTI among stroke patients at the Korle-Bu Teaching Hospital (KBTH) in Ghana. Methods: This was a longitudinal study involving 55 outpatients and 16 inpatients of stroke from the physiotherapy clinic and stroke admission ward of KBTH, respectively. Urine cultures for inpatient subjects were done each day until the patient was discharged. With outpatients, urine specimens were analyzed every week or two for 6 months. Information on demographics and clinical history of the study participants were extracted from their clinical records. Results: Prevalence of UTI among stroke outpatients and inpatients were 10.9% (6/55) and 18.8% (3/16), respectively (p=0.411). Incidence of UTI among stroke outpatients and inpatients were 1.8% (1/55) and 6.3% (1/16), respectively (p=0.125). Overall, 11% (1/9) of the UTI cases among the stroke patients were symptomatic. Severe stroke (OR=17.7, p=0.008) and pyuria (OR=38.7, p=0.002) were identified as predictors of UTI. Escherichia coli was the most common organism implicated in UTI and was susceptible to amikacin, but resistant to augmentin, ampicillin, cefuroxime, co-trimoxazole, meropenem, norfloxacin and tetracycline. Conclusion: UTI is a common complication among both stroke inpatients and outpatients, though it appears to be more common among the former. Stroke severity appears to be the main stroke related determinant of UTI among stroke patients. UTI among stroke patients is mainly asymptomatic and E. coli is the most important aetiological agent.Biography
Eric S Donkor has done his Doctoral degrees in Infectious Diseases and Public Health from the London School of Hygiene and Tropical Medicine, and University of Iceland, respectively. He holds Master’s degrees in Molecular Biology and Animal Microbiology from Birkbeck College, University of London and University of Ghana, respectively. He has received several research fundings and has published 50 peer reviewed articles in the areas of infectious diseases, food safety and environmental health. Currently, he is an Associate Professor of Public Health Microbiology at the University of Ghana, Ghana.
Email: ericsdon@hotmail.com
