Dr. Holbrook | OMICS International
ISSN: 2157-2526

Journal of Bioterrorism & Biodefense
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Dr. Holbrook

Dr. Holbrook is a senior scientist at the IRF-Frederick and also serves as the high-containment supervisor with responsibility for overseeing all research activities within the Biosafety Leve (BSL)l-4 facility. Dr. Holbrook is the former director of the Shope BSL-4 laboratory and the emerging and high risk pathogens core at the Galveston National Laboratory at the University of Texas Medical Branch and was an associate professor in the department of pathology. Dr. Holbrook has been working in the field of arbovirology since 1998 and with BSL-4 pathogens since 2003.


Dr. Holbrook has been working in the field of arbovirology since 1998 and with BSL-4 pathogens since 2003. Dr. Holbrook is considered a worldwide expert in tickborne flaviviruses and has developed significant expertise with all human pathogenic flaviviruses, particularly yellow fever virus.

Dr. Holbrook has also developed practical expertise with most BSL-4 pathogens, with experience working with Nipah and Hendra viruses, filoviruses, Rift Valley fever virus, and highly pathogenic arenaviruses.

Dr. Holbrook’s work has included the development of diagnostic agents as well as the testing of a number of different vaccines and chemotherapeutic agents against BSL-3 and BSL-4 viruses, in addition to extensive research experience in viral pathogenesis, viral immunology, viral protein expression and characterization, viral structure, and molecular virology.

Dr. Holbrook has served as principal investigator, co-investigator, and consultant on a number of National Institutes of Health-supported grants and contracts.

Research Interest

tickborne flaviviruses,human pathogenic flaviviruses, particularly yellow fever virus, development of diagnostic agent and testing of various vaccines.

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