Hidetaka Torigoe | OMICS International
ISSN: 2161-0681

Journal of Clinical & Experimental Pathology
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Hidetaka Torigoe


Establishment of Cellular Quiescence Together with H2AX Downregulation and Genome Stability Maintenance

H2AX is required for genome stability. In response to DNA double-strand breaks (DSBs), H2AX is rapidly phosphorylated to form γH2AX foci, which mediate DNA repair and checkpoint signaling. This process is regulated by modifications and molecular interactions of H2AX. In addition, the rapid stabilization of H2AX in response to DSBs facilitates ... Read More»

Yusuke Matsuno, Hidetaka Torigoe and Ken-ichi Yoshioka

Mini Review: J Clin Exp Pathol 2017, 8: 335

DOI: 10.4172/2161-0681.1000335

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article