Blood Metal Concentrations And Adverse Pregnancy Outcomes; Study In Which Trimester Could Be More Appropriate? | 2837
Journal of Community Medicine & Health Education
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Pregnancy is a unique period in women life. Fetal exposed to toxicants during this period can affect his/her health for long-life.
Although, exposures to metal have sharply decreased in general population and workers, there is not a clear cut-off-point
between toxic and safe levels for many of them. On the other word, many of pregnant women are not exposed to high levels of
toxic metal to show clear clinical symptoms, but their fetuses may suffer several adverse effects that may not be detectable before
or at the time of delivery. Unfortunately, there are not sufficient studies about metal toxicities and pregnancy outcomes due to
many difficulties, such as availability of pregnant subjects for survey, high rate of follow up loss, and various environmental and
endogenous (bones) sources of exposure to metal. As a result, a critical question be considered ?What study method is better
to obtain metal effects on pregnancy?? Since it is easy to conduct, many researchers are gathering blood samples and data at the
time of delivery. However, measurement of metal concentrations and pregnancy outcomes at this period may not be because
gestational outcomes develop several weeks before birth and metal concentrations change during a few weeks by changing in
amount of exposure. Therefore, multiple blood samples should be done throughout pregnancy. Although, this study method
needed a significant research found and researcher efforts.
Dr. Mohsen Vigeh obtained Ph.D. degree in Social Medicine, the University of Tokyo, Japan, and completed medical doctorate course in Faculty of
Medicine, Tehran University, Iran. He had been working for Tehran University of Medical Sciences for several years and currently is scientific staff of
the National Institute of Occupational Safety and Health, Japan. He has collaboration with several local and overseas universities/institute and does
peer review of some journals. Dr. Vigeh's research interest is ?reproductive toxicology? and ?urban air pollution?.
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