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Benzimidazoles are core scaffolds in numerous pharmacologically active compounds. Their synthesis typically involves acid-catalyzed condensation of o-phenylenediamine with carboxylic acids or aldehydes under batch conditions, often resulting in low atom economy and high energy use. This study presents a continuous flow process for benzimidazole syn... Read More»
: J Mol Pharm Org Process Res 2025, 13:269
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