A Non-concurrent Cohort Study On The Use Of Euphorbia Hirta (LINN) In Dengue Fever: Patient?s Selected Clinical And Hematologic Responses | 17891
Epidemiology: Open Access
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engue Fever emerged as major problem in the Philippines and in endemic countries across the world. The absence of
chemotherapeutic agents against Dengue virus generated interest on the use of
, a folk remedy, in Dengue
management. This study aims to document the use of
among Dengue patients and to determine differences
in platelet, WBC counts between subjects who had taken
preparation in comparison to those who did not.
This non-concurrent cohort study included forty-six subjects who had taken
(cohort ) and 47 subjects as
the control group. Focused group discussion (FGD) on the use of
was done. Clinical manifestations, platelet,
hematocrit, white blood cell counts and demographic information were extracted from hospital records.
The course of illness of subjects has conformed with the classical pattern of Dengue fever. The FGD revealed varied use
among the cohort. Mean platelet, WBC counts did not show statistically significant differences between
the groups ( t-test >0.05) when controlled for day of illness. However, the percentage change between the groups differed. The
expected initial drop in platelet was 2 to 3 times slower and the expected rise beginning day 5 to 6 were twice greater in the
cohort compared to the control group. The beneficial effect of
rests on the degree of change in platelet levels
experienced by the subjects. This study paves the way for further analytic studiessuch that the conformed usage of
?s medical properties can be documentedand might be standardized for practical application.
Georgina T. Paredes completed her medical degree at the University of the East, Ramon Magsaysay Memorial Medical Center (UERMMMC), Philippines,in 1973.
She obtained her DTMH and MPH from the Incorporated School of Tropical Medicine & Hygiene, University of Liverpool(UK,1986) and the Braun School of Public
Health, Hebrew University(Jerusalem, 1988) respectively. She was former Dean of Medicine, director of research at UERMMMC. She is currently a full professor in
Preventive and Community Medicine. Serves as consultant for research projects at UERMMMC, Department of Health and Philippine Council for Health Research
and Development.She has published more than 20 papers in reputed journals and has made research presentations in various conferences.
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