AN ATTEMPT TO CALCULATE THE PREVALENCE OF CHRONIC HEPATITIS C INFECTION IN TUSCANY USING ADMINISTRATIVE DATA | 55711
Epidemiology: Open Access
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Introduction: Ansaldi et al. (2005) showed an anti-Hepatitis C virus (HCV) antibody prevalence of 2.7% in the Italian
population. Aim of this study was to evaluate this prevalence in Tuscan population that was know and unknown to the Tuscan
Regional Health Service in 2014 Methods. To evaluate people infected with HCV known to the Regional Health Service we used
the Tuscany Health administrative data. We identified people with a Hepatitis C exention code (070.54), resident in Tuscany.
Through the universal code attribuited to each resident, these patients were matched with hospital admission codes, identified
by the International Classification of Diseases, Ninth Revision (ICD-9) Clinical Modification (such as “acute hepatitis” ICD9-
CM: 070.41 and 070.51; “chronic hepatitis” 070.44 and 070.54; “hepatocellular carcinoma” 155.0; “cirrhosis” 571.5), with codes
for dispensing drugs to patients by local and hospital pharmacies (Ribavirin J05AB04). Individuals were considered only once.
To evaluate HCV population unknown to Regional Health Service we used the Capture-Recapture analysis.
Results: Living people as at 12.31.2014 with HCV exention codes were 14.810. Patients treated with Pegilated interferon+Ribavirin
in the last 10 years were 6635. The total hospital admission in the last 15 years was 18,773. After data linkage the total number
was 29.437. After applying the Capture-Recapture analysis the number of unkown HCV infected people was 29.963. Therefore
the total number of chronic HCV infected people was 56,940.
Conclusion: Tuscan administrative data were in line with the serological prevalence of some research studies and they outlined
the high prevalence of chronic HCV infection.
In 2001 Cristina Stasi graduated in Medicine and Surgery at the Catholic University of “Sacro Cuore”, Rome. In 2006 she specialized in Gastroenterology at the University of Pisa. From 2006 to 2009 she took part in clinical research projects at the University Hospital “Careggi”, Florence. At the same time she improved her knowledge in Study Design, Management of Clinical Research Project, Statistics, Epidemiology. In 2013 she received her PhD in Experimental and Clinical Medicine from the University of Florence. She published more than 40 papers in reputed international journals and she has been serving as an editorial board member of some international journals.