alexa First Results Of A Pre-planned Interim Analysis Of A National Multicenter Patient Reported Outcome Study (PRO-Bra) In Breast Reconstruction Following Mastectomy With Titaniferously Coated Polypropylene Mesh (TiloopBra) | 66957
ISSN: 2572-4118

Breast Cancer: Current Research
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5th World Congress on Breast Cancer
June 15-17, 2017 London, UK

Stefan Paepke
Technical University of Munich, Germany
Posters & Accepted Abstracts: Breast Can Curr Res
DOI: 10.4172/2572-4118-C1-006
Abstract
Introduction: In the majority of interdisciplinary breast centers of Germany implant based, mesh-supported operations constitute a total of approximately 50-60% of reconstructive techniques. The BreastQ is the most valid and reliable measurement of quality of life aspects in important domains used in clinical routine. Material & Method: Because the patient reported outcome is the most relevant factor reflecting the overall satisfaction from a patient perspective a prospective surveillance study with BreastQ-scales at 12 months as primary endpoint was conducted (2013) and ended 7/2016 with full recruitment (n=267). A pre-planned analysis of the first 60 pts with completion of the BreastQ after 6 months was done. Results: Almost all surgeries were primary reconstructions (96.6%) and nipple-skin-sparing mastectomies (97.1%). The most frequent incision was inframammary (n=115), followed by T-shaped (n=45). The average of the pts was 50 y (19-77), BMI was 22 (17-33), 77.3% were non-smokers. Percentage of neoadjuvant chemotherapy was 23% of prior radiotherapy was 12%. Radiotherapy showed no significant influence of the BreastQ. Severe events occurred in 46 cases. The most frequent complications were necrosis (n=12), hematoma (n=12) and 9 pts were dropped out. The mean score of BreastQ was equal pre and postoperative after 6 months (67+/-16 to 65+/-15) satisfaction with breast from 67+/-22 to 61 +/-14; psycho-social well-being from 71+/-17 to 73+/-18, sexual well-being from 62+/-17 to 60+/-19, satisfaction with outcome was 75+/-18 and satisfaction with surgeon 90+/-15. 88.3% were very satisfied, 10.0% somewhat satisfied, only 1.7% somewhat dissatisfied and 0% very dissatisfied.
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