alexa

GET THE APP

Dersleri yüzünden oldukça stresli bir ruh haline sikiş hikayeleri bürünüp özel matematik dersinden önce rahatlayabilmek için amatör pornolar kendisini yatak odasına kapatan genç adam telefonundan porno resimleri açtığı porno filmini keyifle seyir ederek yatağını mobil porno okşar ruh dinlendirici olduğunu iddia ettikleri özel sex resim bir masaj salonunda çalışan genç masör hem sağlık hem de huzur sikiş için gelip masaj yaptıracak olan kadını gördüğünde porn nutku tutulur tüm gün boyu seksi lezbiyenleri sikiş dikizleyerek onları en savunmasız anlarında fotoğraflayan azılı erkek lavaboya geçerek fotoğraflara bakıp koca yarağını keyifle okşamaya başlar
Mitocryptides: A Novel Family Of Neutrophil-activating Peptides Hidden In Mitochondrial Proteins And Their Accumulative Signaling Mechanisms | 5420
ISSN: 2157-2526

Journal of Bioterrorism & Biodefense
Open Access

Like us on:

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
Google Scholar citation report
Citations : 473

Journal of Bioterrorism & Biodefense received 473 citations as per Google Scholar report

Indexed In
  • CAS Source Index (CASSI)
  • Index Copernicus
  • Google Scholar
  • Sherpa Romeo
  • Open J Gate
  • Genamics JournalSeek
  • Academic Keys
  • JournalTOCs
  • ResearchBible
  • China National Knowledge Infrastructure (CNKI)
  • Ulrich's Periodicals Directory
  • RefSeek
  • Hamdard University
  • EBSCO A-Z
  • OCLC- WorldCat
  • SWB online catalog
  • Publons
  • Geneva Foundation for Medical Education and Research
  • Euro Pub
Share This Page

Mitocryptides: A novel family of neutrophil-activating peptides hidden in mitochondrial proteins and their accumulative signaling mechanisms

International Conference on Biothreats & Biodefense

Hidehito Mukai

ScientificTracks Abstracts: J Bioterr Biodef

DOI: 10.4172/2157-2526.S1.002

Abstract
Various functional proteins and physiologically active peptides are firstly synthesized as precursor proteins and matured by specific proteolytic cleavages of them. These proteins and peptides are then degraded by various proteases to inactivate. During these maturation and degradation processes, many fragmented peptides are simultaneously produced, but their physiological roles have not been well elucidated. Recently, we discovered novel bioactive peptides produced from mitochondrial proteins including cytochrome c oxidase subunit VIII, cytochrome b, and cytochrome c which efficiently activate neutrophils. We also found the presence of many neutrophil-activating peptides produced from various mitochondrial proteins. We named such bioactive peptides hidden in protein structures ?cryptides? and those cryptides that are produced from mitochondrial proteins ?mitocryptides?. Here, we report comprehensive identification of various mitocryptides utilizing bioinformatic strategies. We also present the characterization of novel accumulative signaling mechanisms in which many cryptides sharing similar physicochemical properties but having different amino acid sequences cooperatively regulate cellular functions
Biography
Hidehito Mukai received his Ph.D. degree in Applied Biochemistry from the University of Tsukuba in 1990. He advanced his career by working at UT Southwestern, University of Tsukuba, MITTI-NEDO Project at JT, Mitsubishi Kagaku Institute of Life Sciences, and Kyoto Pharmaceutical University. He is currently Principal Investigator of Laboratory of Peptide Science and Associate Professor of Nagahama Institute of Bio-Science and Technology. His main research interests are the discovery of "cryptides", novel endogenous regulatory peptides hidden in protein structures, and their "accumulative" signaling mechanisms.
Top