alexa Natural Extracts From Marine Environment : A Source Of Anticancerous Compounds | 9574
ISSN: 2155-9910

Journal of Marine Science: Research & Development
Open Access

Like us on:

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Natural extracts from marine environment : A source of anticancerous compounds

International Conference on Oceanography & Natural Disasters

Rashmiranjan Behera, Raghunath Satpathy, Rajesh Ku. Guru and Biswajit Nayak

Accepted Abstracts: J Marine Sci Res Dev

DOI: 10.4172/2155-9910.S1.004

Abstract
Due to the high side effect of synthetic product researchers studied extensively on the secondary metabolites from Marine sources which can be utilized as potential drugs. Another reason for searching marine source is the biodiversity of a source which is abundant. Researchers from FAU Harbour branch able to discover drugs from marine sources which are very effective against deadly disease like Cancer, Alzheimer's disease, ocular diseases & other inflammation. Basically the secondary metabolites produced by marine animals like sponge, coral, algae are very effective. Here we can take some example: Ziconotide from cone snail used for treatment of pain ( USFDA approved-2004), Trabectedin ( European Union approved), spongouridine and spongothymidine from a sponge ( Cryptotheca crypts ), were used for cancer treatment. Some other antitumor compound include: Aplidine from tunicate ( Aplidium albicans ) effective against renal & medullary thyroid carcinoma & Neuro endocrine tumors, Agelasphins from an Okinawan sponge, Bryostatin I from the Bulgula neritina , Discodermolide, from sponge Discodermia dissoluta . Dolastatins from the Indian Ocean sea hare Dolabela having anti neoplastic activity , halichondrin ( Halichondria okadai constituent ) has tumor inhibitory activity . Spisulosine from Spisula polynyma has antiproliferative activity against cancer cell lines. Squalamine from the dogfish shark, ( Squalus acanthias ) has anti angiogenesis activity . Ecteinascidin from tunicate ( Ecteinascidia turbinata ) act against sarcomas. From a report of FDA Currently 2 anticancer drugs : Cytarabine & Eribulin approved by the FDA are in phase III trial, 118 Marine natural products are in preclinical trial, 22 during clinical trial & 3 on the market.
Biography
Top