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he Socioeconomic Achievement Pressure hypothesis is presented as the environmental cause of Hodgkin lymphoma across
the human lifespan and across all ethnicities. This claim is supported by an almost complete coverage of the Hodgkin
lymphoma epidemiology with this hypothesis. Based on this hypothesis I contend that the risk for Hodgkin lymphoma can be
explained by excess achievement and intellectual pressure in specific individuals because they find it hard to fulfill or to comply
with the high standards of socioeconomic and/or intellectual requirements of their family, community or peers. The prolonged
and intense cognitive stress might ultimately lead to Hodgkin lymphoma development. Thus intellectual and cognitive stress
appear to be the causal sociocultural mechanisms in Hodgkin lymphoma development. Cognitive and intellectual stress appear
to cause deregulations of the lymphatic system. The experienced severity of cognitive stress determines what kind of lymphoma
the patient will develop. Both intensity and the duration of exposure to cognitive stressors are crucial in lymphoma development.
The personal characteristics of the patient are crucial to understand the incidence of Hodgkin lymphoma. Hodgkin lymphoma
epidemiology also provides for the causal mechanisms how family dynamics really work. It also clarifies that sociocultural
mechanisms rather than genetic explanations appear to be the causal mechanisms underneath the similarities in behavior and
preferences of identical twins. This research provides important clues to conduct more thorough and conclusive research on
twins, family dynamics and lymphomas in animals.
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