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Doo-Sup Choi is a molecular biologist and neuroscientist. He graduated from the Department of Biochemistry at Yonsei University in Seoul, Korea with BS (1988) and MS (1990). Dr. Choi worked for Samsung (CJ Foods and Chemicals) from 1991 to 1993 and following that, completed his Ph.D. at the Louis Pasteur University in Strasbourg, France in 1997. He carried out his Ph.D. research on the neurobiological and developmental roles of novel serotonin 5-HT2B receptors in mice. He performed a two-year postdoctoral research in the field of neuropharmacology of addiction (1997-1998) in the Department of Biopharmaceutical Sciences at University of California San Francisco (UCSF). Following that, Dr. Choi joined the Ernest Gallo Clinic and Research Center and the Department of Neurology at UCSF as a staff research scientist (1999-2004) and then a junior faculty member (2004-2005). He carried out groundbreaking research on the genetic, neurobiological, and behavioral aspects of alcoholism using several mouse genetic models that he generated including PKCε inducible transgenic, neuron-specific PKCε transgenic, PKCδ null, and ENT1 null mice. Dr. Choi joined the College of Medicine, Mayo Clinic in 2005 and has established an innovative and cutting-edge research program by combining mouse genetics, behaviors, proteomics, neurochemistry, and imaging. Currently, his main research focuses on adenosine and glutamate signaling in neuron-glia interaction and its implication in alcoholism.
Neuroscience, Molecular Biology
The research interests of Doo-Sup Choi, Ph.D., focus on neurobehavioral and addictive disorders, which cause a substantial socio-economic burden to society. Dr. Choi's laboratory utilizes a combination of genetics, pharmacology, proteomics, metabolomics, brain imaging and behaviors to identify clinically useful therapeutic targets of a variety of neurological and psychiatric disorders.
Research Article: J Addict Res Ther 2011, S4
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