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In Dr. Lowe’s state-of-the-art “Biomaterials for Translational Research Laboratory”, the research features innovative bionanotechnology, drug delivery, gene therapy, tissue engineering, and biosensor. The research activities include rational design and synthesis of multi-stimuli-responsive polymeric biomaterials including nanogels, branched nanoparticles, hydrogels and thin films; characterizations of the mechanisms by which the designed biopolymers regulate targeted and sustained delivery of drugs, proteins and genes, promote cell growth, and provide biosensing; and in vitro and in vivo studies of the bioefficacy of these biomaterials. The ultimate goal of the research in Dr. Lowe’s lab is to develop novel biomaterials that can provide exquisitely sensitive, selective, non-toxic, biodegradable and responsive platforms to target therapeutic agents to the sites of ocular, central nervous, cancerous and musculoskeletal lesions.
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