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Yazen M Alnouti is an Assistant Professor in the Department of Pharmaceutical Sciences, University of Nebraska Medical Center. He worked as a Research Assistant Professor in the Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center. he received his Post Doctorate from University of Kansas Medical Center. He was selected by Selected by “Who’s Who in America” as a scientist with outstanding achievements in the year 2009. He has a Professional membership in American Association of Colleges of Pharmacy (AACP). He experienced as a Teaching & Research Assistant in the College of Pharmacy, University of Georgia. His highlights of Research expertise include Drug Metabolism and Disposition, High-Throughput Bioanalytical Chemistry and Pharmacokinetics.
His research focuses on the application of bioanalytical chemistry, in vitro models such as microsomes and stably-transfected cell lines, and in vivo animal models such as knock-out mice, to support ADMET (absorption, distribution, metabolism, excretion, and toxicity) and pharmacokinetics studies. This is a technique-driven enterprise; therefore liquid chromatography-mass spectrometry (LC-MS) is heavily applied in our research. Another area of interest is the study of bile acid metabolism, homeostasis, and toxicity, with a particular interest in the role of sulfation, a phase II metabolic pathway, by the sulfotransferase (SULT) enzymes, in controlling bile acid homeostasis.
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