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Chang-Guo Zhan is Professor of Pharmaceutical Sciences in the College of Pharmacy, University of Kentucky. Dr. Zhan received a Ph.D. in Chemistry from University of Notre Dame and a Ph.D. in Science from Institute for Molecular Science (IMS), Japan. Dr. Zhan performed his postdoctoral research training as a Postdoctoral Research Scientist at Department of Medicine, Columbia University. Dr. Zhan joined the UK College of Pharmacy faculty as Associate Professor in July 2003 and was promoted to Professor in July 2007. Dr. Zhan was elected as Fellow of the American Association of Pharmaceutical Scientists (AAPS) in 2010. Dr. Zhan is a winner of 2005 Emerging Computational Technology Prize, American Chemical Society (ACS) Division of Computers in Chemistry. He has served as Chair of AAPS Computational Drug Design Focus Group and on AAPS National Biotechnology Conference Programming Committee.
Dr. Zhan’s main research interest is drug design and discovery through integrated computational-experimental studies. Drugs designed and discovered in Dr. Zhan’s lab are either small molecules (as inhibitors of enzymes or agonists/antagonists of receptor proteins or DNA-binding molecules etc.) or engineered proteins (mutants with significantly improved biological functions and/or increased circulation time in the body).
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