Journal of Addiction Research & Therapy
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espected investigators suggest that addiction is multiply determined and cannot be adequately treated using the narrow
biomedical model of prescribing one medication or one psychosocial treatment. They recommend integrating evidence-
based treatments because combining distinct but compatible treatments creates a synergistic effect that increases treatment
effectiveness. Highly effective treatments are especially needed among patients with co-occurring psychiatric disorders because
comorbidity impedes recovery.
One clinical trial by the National Institute on Drug Abuse Clinical Trials Network used a 12-Step facilitative intervention in
a dual disorders addiction clinic. Entitled Stimulant Abuse Groups to Engage in 12-Step Programs (STAGE-12), the intervention
was added to Intensive Outpatient Therapy (IOP) and compared to IOP alone (Treatment As Usual, TAU) (N=421). Compared to
TAU, STAGE-12 participants had greater odds of being stimulant abstinent during the 8-week treatment phase. However, among
STAGE-12 participants, those who had not achieved abstinence reported more drug use. STAGE-12 participants had lower drug-
related consequences on the Addiction Severity Index (ASI) than TAU participants. No other differences were found.
Another study at the University of Pittsburgh Medical Center investigated the affect of a Contingency Management (CM)
intervention during IOP (N=160). Participants were systematically exposed, or not exposed to a CM intervention for one year.
Participants exposed to CM spent more time in IOP treatment. Importantly, time in treatment mediated the relationship between
exposure to CM and drug free days.
Although the findings are not consistently positive, outcomes from these studies indicate that combining other treatments
with IOP can be more effective than IOP alone
Thomas M. Kelly earned his Ph.D. at the University of Pittsburgh in 1996 and is an Associate Professor of Psychiatry at the University of Pittsburgh
School of Medicine. He is currently Director of the Adolescent Substance Abuse Treatment Service at the University of Pittsburgh Medical Center
and is a Co-Investigator with the Appalachian Tri-States Node of the National Institute on Drug Abuse Clinical Trials Network. He has conducted
research among adolescents with alcohol-related injuries and among adults with dual substance and psychiatric disorders. He has published over
20 first- authored papers in the fields of psychiatry and addiction
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