Empirical Derived AUD Sub Types In The US General Population | 4218
Journal of Addiction Research & Therapy
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The clinical expression of Alcohol Use Disorders (AUDs) has been shown to be heterogeneous, on a bio-
psycho-social scale. The concept of alcoholic typologies, arising from such complexities, is not new,but to date, despite some
commonalities, there is no consensus as to the number or dimensions of AUD types. This study aimed to identify subtypes of
AUD in a general population sample based on DSM 5 and four severity / vulnerability criteria.
Data from 22 177 current drinkers in the National Epidemiologic Survey on Alcohol and Related Conditions
(NESARC) Wave 2 (2004-2005)were assessed by latent class analysis (LCA) in order to identify homogeneous subtypes and
further validated by multivariate regression analysis on a range of socio-demographic (age, gender, race, income, education,
marital status) background (non-fatal injury, criminality) clinical (liver cirrhosis, mood, anxiety, substance use,personality)and
clinically orientated (alcohol consumption frequency, nicotine intake) variables.
LCA identified a four-class solution based on a severity gradient, three AUD classes and one non-problematic drinking
class, as the most parsimonious description of the data and external validation of this solution was supported by differences
between classes on the covariates.
Three distinct subtypes of AUD were extracted, distinguished by DSM 5 criteria, consumption levels, family and
treatment seeking history, with further covariate validation. These subtypes have high clinical utility, enhance AUD classification
and add to our understanding of AUD trajectories,prevention and treatment
Martina is currently a second year PhD candidate at the University of Ulster in Northern Ireland, where she also completed her undergrad studies. The topic of her thesis is The Heterogeneity of Alcohol Use Disorders. She currently has one paper in press and two further papers under review.
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