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Frank C. Barone from 1997 to 2004, leader of GSK course entitled "In Vivo Pharmacology: Animal Research, Disease Models and Drug Discovery" (PR 625; for 3 credits in Thomas Jefferson University Graduate School Catalog). The course was a collaborative work effort of Laboratory Animal Sciences and the Centers of Excellence in Drug Discovery at GlaxoSmithKline. Course continues to be offered at GSK. Course covers animal welfare, surgery, anesthesia, pathophysiology of cardiovascular, metabolic, cancer, pulmonary, inflammatory and infectious diseases with laboratories (i.e., that demonstrate important principles and approaches in drug discovery research including state of the art imaging and molecular biology techniques). Drug discovery research (e.g., for target validation and higher throughput whole animal studies) lectures provide descriptions of disease models and relevancy to human diseases (i.e., translational medicine) and use of surrogates and other biomarkers related to improved outcome from disease.
cardiovascular, cerebrovascular diseases, Integrate Systems Pharmacology/Biology and Translational Medicine into Drug Discovery and Disease Biology Research.
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