GET THE APP
Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers
Mr. Hirai, Research Associate of Genetics, Cell Biology and Development at the University of Minnesota, is an investigator of the Stem Cell Institute and the Minnesota Supercomputing Institute. He received his Ph.D. in Biochemistry from Tokyo Medical and Dental University. He studied muscle stem cell biology and therapy at Stem Cell Institute, University of Minnesota as a postdoctoral fellow. He then studied biochemical analysis of nuclear remodeling in somatic cell nuclear cloning. Recently he fused the transactivation domain (TAD) of MyoD to the pluripotency gene Oct3/4 and radically improved the efficiency of making iPSCs. In addition, fusion of the MyoD TAD to the cardiac transcription factor Mef2c facilitates the direct reprogramming of non-cardiac fibroblasts to cardiomyocyte-like cells.
Dr. Hirai's current research interests are to develop a transdifferentiation strategy and stem cell biology. These studies are expected to contribute to the development of celluar/gene therapy and regenerative medicine. He has been investigating progenitor cells, somatic stem cells and induced pluripotent stem cells (iPSCs) of mouse and human. He continues the research of other regulators necessary for the direct reprogramming and iPSCs reprogramming.
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals