Bas Vroling | OMICS International
ISSN: 2168-9652

Biochemistry & Physiology: Open Access
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Bas Vroling

The Netherlands

Common Pitfalls and Novel Opportunities for Predicting Variant Pathogenicity

The prediction of missense variant pathogenicity is normally performed using analyses of multiple sequence alignments optionally augmented with analyses of the (predicted) protein structure. The most straightforward way, though, is to search the literature to see whether this variant has already been described. Variant data from homologous proteins... Read More»

Tom van den Bergh, Bas Vroling, Remko KP Kuipers, Henk-Jan Joosten and Gert Vriend

Research Article: Biochem Physiol 5: 197

DOI: 10.4172/2168-9652.1000197

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF