Biochemistry & Physiology: Open Access
Open Access

Biography

Cecilia H. Marzabadi received her Bachelor’s degrees (Chemistry and Biology) and Masters degree (Chemistry) from Saint Louis University She earned her Ph.D. in Chemistry at the University of Missouri- St. Louis. Her doctoral research examined the preparation and reactions of glucal halohydrins. Dr. Marzabadi did post-doctoral research at Hunter College/CUNY under the direction of Professor Richard Franck. Her post-doc project looked at the synthesis of 2-deoxysugars using a cycloaddition/ring opening based approach. In 1999, she was appointed as a Clare Boothe Luce Assistant Professor in chemistry at Seton Hall University. She was promoted to Associate Professor in 2005.  In 2006, she was a Visiting Associate Professor at Harvard Medical School in the lab of Dr. Dennis Kasper studying the innate immunology of a novel class of zwitterionic saccharide. Dr. Marzabadi has been the Associate Chair and Director of Graduate Studies for her department at Seton Hall since 2009.

Research Interest

Ms.Marzabadi’s current research interests lie in several areas of synthetic carbohydrate chemistry. Ongoing projects in her lab include:  the synthesis of septanose C-glycosides and septanose sugars by a ring-opening/ homologation/ ring-closing strategy. Methods are also being developed for the synthesis of simplified analogs of zwitterionic sugars to be studies in immunological assays. Small molecule therapeutics are also being developed from carbohydrate beased-heterocycles. An iodoamidation procedure has been developed for the synthesis of carbohydrate-based oxazolines to be studied as glycosidase inhibitors. A Povarov reaction has been used to construct novel carbohydrate-based quinolines for study as anti-cancer and antibiotic agents. Novel cyclopropanated sugars and glycals have been developed that display efficacy in the treatment of epilepsy and chronic pain management

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