Diana L Borgas | OMICS International
ISSN: 2168-9652

Biochemistry & Physiology: Open Access
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Diana L Borgas

Pierre Galletti Research Building, Rhode Island Hospital, 55 Claverick Street, Room 419, Providence

PPAR Agonist Effects on Notch Signaling Mediators in Experimental Chronic Alcohol-Induced Steatohepatitis

Background: Aspartyl-Asparaginyl-Β-Hydroxylase (ASPH) is a downstream target of insulin and IGF signaling and promotes cell motility for liver remodeling and repair. ASPH functions in part by activating Notch and HIF-1α. PPAR agonists can ameliorate steatohepatitis, hepatic insulin resistance, and reduced ASPH expression in experimental a... Read More»

Diana L Borgas, Chetram Deochand, Ming Tong and Suzanne M de la Monte

Research Article: Biochem Physiol 3: 145

DOI: 10.4172/2168-9652.1000145

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF