Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
Google Scholar citation report
Citations : 2287

Journal of Obesity & Weight Loss Therapy received 2287 citations as per Google Scholar report

Journal of Obesity & Weight Loss Therapy peer review process verified at publons
Indexed In
  • Index Copernicus
  • Google Scholar
  • Open J Gate
  • Genamics JournalSeek
  • Centre for Agriculture and Biosciences International (CABI)
  • RefSeek
  • Hamdard University
  • EBSCO A-Z
  • OCLC- WorldCat
  • SWB online catalog
  • CABI full text
  • Cab direct
  • Publons
  • Geneva Foundation for Medical Education and Research
  • Euro Pub
  • University of Bristol
  • Pubmed
  • ICMJE
Share This Page

Assessment of circulating adipokine levels in type 2 diabetes mellitus in Lagos, Nigeria

International Conference and Exhibition on Obesity & Weight Management

Temitope Oshodi

ScientificTracks Abstracts: J Obes Wt Loss Ther

DOI: 10.4172/2165-7904.S1.002

Abstract
Background: Type 2 diabetes remains a global concern with its numerical increase occurring in developing countries which include Nigeria and adipose tissue-secreted factors called ?adipokines? are involved in energy homeostasis and regulation of glucose and lipid metabolism. Hence, this study was undertaken with the aim of investigating adipokine levels in the Type 2 Diabetes Mellitus. Materials: This is a cross sectional study conducted in Lagos University Teaching Hospital (LUTH), a700 bed tertiary centre in the city of Lagos, Southwest Nigeria. 53 diabetic subjects with mean± standard deviation (56.72±10.44) and 27 non-diabetic controls (38.67±9.63) were recruited into the study. Fasting blood Glucose (FBG), glycosylated haemoglobin (HbA₁C), leptin, and resistin were assayed. Body mass index (BMI) was also measured. Results: Mean BMI was higher but not statistically significant in diabetics than in non diabetics (diabetics 28.77±5.35; non diabetics 27.38±6.04; p > 0.05). This corroborates other studies that the higher level of adiposity predisposes higher level of FBG and HbA1C and to the incidence of DM as a result of the effect of increasing fat mass on insulin sensitivity [1,2].Resistin was significantly higher in diabetics (diabetics 31.26±2.5; non diabetics 16.61±2.16; P < 0.01) compared to non-diabetics. Leptin correlated very strongly with BMI (r = 0.620, p< 0.0001) and was significantly higher in females than males (female: 9.72±1.70; male: 1.79±0.54; p < 0.0001) which agrees with the study conducted by Zimmet and Thomas [3]. Conclusion: This study concludes that circulating adipokines have variable effect on the glucose and fat metabolism. BMI and resistinlevels were higher in diabetics. Leptin was found in this study to correlate very strongly with BMI (adiposity). There was also a strong gender dependence observed as leptinlevel was signficantly higher in females than males.
Biography
Relevant Topics
Top