Journal of Obesity & Weight Loss Therapy
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The objective of this study was two-fold: 1) to investigate whether weight loss is associated with a reduction in perceived
need for Total Knee Replacement surgery due to decrease in knee pain and improvement in function, 2) to identify what
percentage of weight loss is associated with reduction in knee pain to a point where the need for surgery could be prolonged or
alleviated. 34 subjects were recruited into the study. Women between 40 and 65 years old with morbid obesity (BMI ≥ 35 kg/
m2) and osteoarthritis of the knee were pre-selected. Participants completed the Western Ontario and McMasters (WOMAC)
Universities index, The Short Form Health Survey (SF-36); 6-Minute Walk Test and Timed Up and Go at baseline and participants
were enrolled into a weight loss program, for a 6 month period. Repeated measures ANOVA revealed that at 6 weeks of diet the
mean body weight reduction of 9.5%, was followed by a significant reduction (p=.015) in WOMAC scores and (p=.038) SF-36
sub score of physical function. At 3 months of diet a significant reduction of 16.5% in body weight corresponded to a significant
decrease of 37% in knee pain and 50% in perceived need for surgery.
These results suggest that an initial loss of 16.5% of body weight for obese individuals was significant enough to reduce pain
and postpone patient?s intent to have surgery in 50%.
Kamary Coriolano is currently completing his PhD at Queen?s University, Canada. He has a unique set of competencies to enable the achievement of
present and future objectives. He was trained as a Physiotherapist in Brazil and obtained two Master?s degrees in Canada that combine knowledge
achieved through academic work in rehabilitation and health care management. His current and main focus is to establish proper conservative
methods to improve quality of life and promote behavioral change particularly for obese individuals who require total knee replacement surgery
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