Effect Of A Grape Phenolic Concentrate On Plasma Cholesterol Levels In Humans | 14793
Journal of Obesity & Weight Loss Therapy
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Several studies pointed atherosclerosis as the main cardiovascular disease, the leading cause of morbidity and mortality among
adults in Western countries. There are a lot of studies has pointed that grape compounds as red wine or grape concentrate,
rich in polyphenols, has possible antioxidant effect leading to decrease of cellular events of atherosclerosis and reduction of
cardiovascular risks. This paper proposes an investigation of the effects of a 28 days diet of 70 mg daily of a grape juice concentrate
rich in anthocyanidins, the G8000, on total cholesterol and its fractions, LDL, VLDL and HDL, and triglycerides, and in plasma
enzymes biomarkers of muscle injury, CK, CK-MB and LDH in normal human subjects. The results showed decreased levels of
plasma LDL measures, and increased levels of HDL. There are no differences for the other lipid measures. As regard the enzyme
measures we observed decrease of CK_MB and increase of LDH measures, what suggest the antioxidant effect of the G8000. The
results suggest that the G8000 can be considered as a tool to decrease cardiovascular diseases risks.
Rogerio Correa Peres has completed his Ph.D. at the age of 30 years from Universidade Federal de Sao Paulo-UNIFESP and he is finishing his
postdoctoral studies from Universidade Federal de Sao Paulo-UNIFESP. He is the Physiology Professor of Universidade Monte Serrat-UNIMONTE
and Catholic University of Santos-UNISANTOS. He has published 5 papers in reputed journals and 1 book chapter, and is serving as reviewer for
more than 6 journals.
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